「ダークネス 2」では、マフィアのドンとなった主人公ジャッキーの持つ、“ダークネス”の力を狙い、黒魔法結社＜ブラザーフッド＞が襲いかかってくる。ジャッキーは封印していたダークネスの力を解放、血みどろの戦いを繰り広げていく
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